Upstream Bio, Inc. Common Stock UPB

$2.76 -18.10% at last close

Analyst Consensus

Consensus Rating
Moderate Buy (4 Buy · 2 Hold · 0 Sell)
Average Price Target
$29.67
Implied Upside
+974.9%
Price Target Range
$9.00 – $50.00
Analysts (12 mo)
6

Recent Analyst Actions

DateFirmActionRatingPrice Target
2026-09-02
HC Wainwright & Co.Matthew Caufield
Reiterates Buy $36
2026-08-14
JP MorganTessa Romero
Maintains Neutral $8 → $9
2026-08-12
Truist SecuritiesDanielle Brill
Maintains Buy $43 → $25
2026-06-12
JP MorganTessa Romero
Downgrades Overweight → Neutral $35 → $8
2026-06-03
HC Wainwright & Co.Matthew Caufield
Initiates coverage on Buy $36
2026-05-14
MizuhoJoseph Catanzaro
Maintains Outperform $51 → $50
2026-03-27
Evercore ISI GroupCory Kasimov
Downgrades Outperform → In-line $40 → $15
2025-12-18
MizuhoJoseph Catanzaro
Initiates coverage on Outperform $51
2025-12-02
LifeSci Capital
Initiates coverage on Outperform $43
2025-11-18
Evercore ISI GroupCory Kasimov
Initiates coverage on Outperform $40
2025-10-14
Truist SecuritiesDanielle Brill
Initiates coverage on Buy $47
2024-11-05
JP MorganTessa Romero
Initiates coverage on Overweight $38
2024-11-05
William BlairMatt Phipps
Initiates coverage on Outperform —
2024-11-05
TD CowenYaron Werber
Initiates coverage on Buy —
2024-11-05
Piper SandlerYasmeen Rahimi
Initiates coverage on Overweight $75

Ratings and price targets reflect each firm's most recent published action. Consensus combines the latest call from every covering firm over the past 12 months; price targets are typically 12-month horizons.

Key Stats

Last Close
$2.76
Market Cap
$151.17 million
52-Week Range
$2.74 – $33.68
Average Volume
875K shs

Data is delayed and provided for informational purposes only. Not investment advice. See our disclaimer.